Skip to content
    back
    Drag image Interact with fingers
    vial-dry
    cleaning
    Cleaning & Sterilization

    Syntegon offers internal and external cleaning machines for vials and other containers. Once the vials have been pre-cleaned with Water for Injection (WFI), our HQL tunnel ensures safe and reliable sterilization and depyrogenation with dry heat.

    Learn more
    filling-and-closing
    Filling and Closing

    A wide range of technologies, including valve piston and peristaltic pump, mass-flow and time-pressure filling, make sure you can fill your products in a highly customized way. Tool-less format changes and filling stations with a variable number of filling heads increase the flexibility of your filling processes.

    Learn more
    capping
    Capping

    Capping Continuous capping with high speeds completes the safe and reliable closing process. 100 % in-process control (IPC) check weighing and inline inspection systems for empty vials, stopper position or crimp quality further increase product quality.

    Learn more
    external-cleaning
    External cleaning

    Following filling and capping, the vials can be transferred to our RAN external cleaning machine, which makes sure that no particles adhere to the outer sides of the vials.

    Learn more
    barrier
    Barrier Systems

    Barrier Systems Syntegon has established a comprehensive portfolio, including open RABS, closed RABS, containment and isolator systems.

    Learn more
    inspection
    Inspection

    State-of-the-art technologies for visual inspection and container closure integrity testing (CCIT), including high voltage leak detection (HVLD), static division (SD) and headspace analysis (HSA).

    Learn more
    The right match
    for your needs

    These solutions meet your fill-finish requirements for dry vials

    Pharmaceutical powders form the basis of numerous antibiotics and other medicines that are essential for comprehensive medical care. The finely ground-active ingredients generate dust easily. Hence, machine operators must be protected from these sometimes toxic or potent ingredients. Syntegon has been supporting customers in pharmaceutical powder filling for more than 60 years. Our experts will be happy to pass on their expertise to you, too!

    membrane-based

    Pure media & formulation systems

    Pure media are essential utilities in parenteral pharmaceutical manufacturing. From “cold” membrane-based systems for the generation of PW, HPW, and WFI and “hot” distillation-based systems for the production of WFI and PS, to the corresponding storage systems and distribution to the point of use, our portfolio provides a comprehensive and seamlessly integrated pure media infrastructure. For your drug product compounding needs, in turn, we also offer formulation systems. Comprising a wide range of process vessels and their automation as well as all associated peripherals including media supply and CIP/SIP units, our modular processing systems truly are “the perfect match for every batch.”

    Learn more
    cleaning

    Cleaning & sterilization

    Sterility matters across the entire aseptic process – before, during and after sterile filling. Syntegon offers internal and external cleaning machines for vials and other containers. Once the vials have been pre-cleaned with Water for Injection (WFI), our HQL tunnel ensures safe and reliable sterilization and depyrogenation with dry heat. Following filling and capping, the vials can be transferred to our RAN external cleaning machine, which makes sure that no particles adhere to the outer sides of the vials; an important factor in protecting operators and healthcare workers.

    Learn more
    filling-and-closing

    Filling and closing

    Our vial filling systems combine flexibility and precision: a wide range of technologies, including auger dosing, pressure vacuum, or slide chamber dosing, make sure you can fill your products in a highly customized way. Tool-less format changes and filling stations with a variable number of filling heads increase the flexibility of your filling processes. Subsequent sealing offers you a variety of methods such as pick and place or continuous stoppering. Continuous capping with high speeds completes the safe and reliable closing process. 100 % in-process control (IPC) check weighing and inline inspection systems for empty vials, stopper position or crimp quality further increase product quality.

    Learn more
    barrier

    Barrier systems

    Aseptic filling is all about product safety – and thus the separation of operators and pharmaceutical ingredients. Isolator technology helps to build this crucial barrier. Syntegon has established a comprehensive portfolio, including open RABS, closed RABS, containment and isolator systems. All solutions are tailored to customer requirements, from machine design and development to on-site installation and validation.

    Learn more
    inspection

    Inspection

    Like any pharmaceutical container, vials require thorough inspection to ensure patient safety. Our wide range of manual, semi and fully automated inspection machines inspects liquid and lyophilized pharmaceuticals for particles and container defects. Thanks to our long-standing inspection expertise, we offer state-of-the-art technologies for visual inspection and container closure integrity testing (CCIT), including high voltage leak detection (HVLD), static division (SD) and headspace analysis (HSA). Moreover, Syntegon provides fully integrated inline inspection solutions for several inspection tasks such as empty vial, crimping and stopper seat inspection.

    Learn more
    Service Agreements
    Service Agreements

    Find out more about our Service Agreements here.

    Learn more
    Digital Solutions
    Digital Solutions

    Find out more about Digital Solutions here.

    Learn more
    Maintenance
    Maintenance

    Find out more about Maintenance here.

    Learn more
    Technical Support
    Technical Support

    Find out more about Technical Support here.

    Learn more
    Modernizations
    Modernizations

    Find out more about Modernizations here.

    Learn more
    Training
    Training

    Find out more about our Training here.

    Learn more
    Expert Services
    Expert Services

    Find out more about our Expert Services here.

    Learn more

    Read our latest news 

    Syntegon at ProSweets: come to experience line competence in confectionery manufacturing and packaging
    28.11.2024
    Syntegon at ProSweets: come to experience line competence in confectionery manufacturing and packaging

    Discover innovative confectionery solutions at ProSweets 2025, booth D045, Hall 10.1. Experience our expertise in sustainable production and packaging.

    More
    Syntegon and Telstar: joining forces for your success
    Syntegon and Telstar: joining forces for your success

    Today marks the beginning of a new chapter in liquid pharmaceutical filling operations! The...

    More
    Discover our Experience & Innovation Centers
    Discover our Experience & Innovation Centers

    At our three modern Experience & Innovation Centers in Weert, Netherlands, in New Richmond, USA and...

    More
    Makat’s NutraGummyFactory gets ‘Highly Commended’ at the World Confectionery Conference 2024
    Makat’s NutraGummyFactory gets ‘Highly Commended’ at the World Confectionery Conference 2024

    Welcome to the NutraGummyFactory, a leader in nutraceutical gummy production. Our team delivers...

    More
    TPR tablet presses from Syntegon: a long history of successful innovation
    TPR tablet presses from Syntegon: a long history of successful innovation

    Discover the TPR tablet compression range from Syntegon, a trusted name in OSD drug manufacturing...

    More
    More Syntegon News
    bosch-02

    Interested in these solutions meet your fill-finish requirements for dry vials?

    Contact us